MOLECULAR PATHOLOGY PROCEDURE, LEVEL 3 (EG, >10 SNPS, 2-10 METHYLATED VARIANTS, OR 2-10 SOMATIC VARIANTS [TYPICALLY USING NON-SEQUENCING TARGET VARIANT ANALYSIS], IMMUNOGLOBULIN AND T-CELL RECEPTOR GENE REARRANGEMENTS, DUPLICATION/DELETION VARIANTS OF 1 EXON, LOSS OF HETEROZYGOSITY [LOH], UNIPARENTAL DISOMY [UPD]) CHROMOSOME 1P-/19Q- (EG, GLIAL TUMORS), DELETION ANALYSIS CHROMOSOME 18Q- (EG, D18S55, D18S58, D18S61, D18S64, AND D18S69) (EG, COLON CANCER), ALLELIC IMBALANCE ASSESSMENT (IE, LOSS OF HETEROZYGOSITY) COL1A1/PDGFB (T(17;22)) (EG, DERMATOFIBROSARCOMA PROTUBERANS), TRANSLOCATION ANALYSIS, MULTIPLE BREAKPOINTS, QUALITATIVE, AND QUANTITATIVE, IF PERFORMED CYP21A2 (CYTOCHROME P450, FAMILY 21, SUBFAMILY A, POLYPEPTIDE 2) (EG, CONGENITAL ADRENAL HYPERPLASIA, 21-HYDROXYLASE DEFICIENCY), COMMON VARIANTS (EG, IVS2-13G, P30L, I172N, EXON 6 MUTATION CLUSTER [I235N, V236E, M238K], V281L, L307FFSX6, Q318X, R356W, P453S, G110VFSX21, 30-KB DELETION VARIANT) ESR1/PGR (RECEPTOR 1/PROGESTERONE RECEPTOR) RATIO (EG, BREAST CANCER) MEFV (MEDITERRANEAN FEVER) (EG, FAMILIAL MEDITERRANEAN FEVER), COMMON VARIANTS (EG, E148Q, P369S, F479L, M680I, I692DEL, M694V, M694I, K695R, V726A, A744S, R761H) TRD@ (T CELL ANTIGEN RECEPTOR, DELTA) (EG, LEUKEMIA AND LYMPHOMA), GENE REARRANGEMENT ANALYSIS, EVALUATION TO DETECT ABNORMAL CLONAL POPULATION UNIPARENTAL DISOMY (UPD) (EG, RUSSELL-SILVER SYNDROME, PRADER-WILLI/ANGELMAN SYNDROME), SHORT TANDEM REPEAT (STR) ANALYSIS